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Made in France · Over 40 years of research Mesotherapy · Biorevitalisation · Skin Quality · Zurich Main Station
Fillmed NCTF® 135 HA: Skin Quality from the Inside – No Filler
Non-cross-linked hyaluronic acid, 12 vitamins, 24 amino acids, co-enzymes, nucleosides and minerals — delivered directly to places creams cannot reach. A strategy for restoring radiance, hydration and skin quality.
5.0★ · 800+ reviews · V-NISSG · Over 40 years of research · Vital Injector 2™
Who is it suitable for?
This treatment is for you if …
NCTF® is one of the most versatile treatments available at alestetics® — whether used as a skin primer before energy-based treatments, as a restorative course of treatment, or as part of a regular skincare regime.
✓
Your skin looks tired, dehydrated or sallow — creams provide short-term hydration, but they don’t penetrate deeply enough.
✓
You’re starting to notice the first fine lines and "creases" — typically caused by dryness, lack of sleep or stress — and you want to improve your skin’s condition rather than just cover them up.
✓
You’re planning to have Vivace® or IPL treatment — and want to prepare your skin properly so that the energy-based treatments can work on regenerated skin.
✓
You have completed a course of treatment and now need the active ingredient layer to consolidate and build on the results.
✓
You want to look fresher, but not different — no extra volume, no altered contours, just better-looking skin.
✓
Are you looking for a seasonal refresh — after winter, after the sun, after a stressful few weeks?.
Not suitable: NCTF® is not suitable for patients with active skin infections, herpes or inflammation in the treatment area, known allergies to any of the active ingredients, autoimmune diseases or those undergoing active immunotherapy, or for those taking blood-thinning medication. It is also contraindicated during pregnancy and breastfeeding. We do not treat patients under the age of 18.
Indications
What NCTF® 135 HA does for your skin.
Eight areas of application in which NCTF® plays a central role in the alestetics® Skin Quality System — from the immediate need for a glow to strategic preparation for intensive treatments.
01
Deep hydration
Non-cross-linked hyaluronic acid binds a thousand times its own weight in water — delivered directly into the dermis, where creams cannot reach.
02
Glow and freshness
Your skin looks well-rested and your complexion fresher — as if you’ve just come back from holiday. The results are visible straight away and become more pronounced with every subsequent session.
03
Fine lines and creases
Lines that are caused by a lack of moisture and stress — typical of Eye area, The Wangen, Neck area. NCTF® cushions it visibly over the depth of the active ingredient.
04
Skin primer before Vivace® or IPL
2–3 NCTF sessions prior to Vivace® RF microneedling or Stellar M22™ IPL provide the ideal preparation for the skin — collagen production begins on a regenerated skin structure.
05
Consolidation following energy treatments
2–3 NCTF sessions following Vivace® or IPL enhance and stabilise the results. The improvement in skin quality lasts visibly longer.
06
The first signs of ageing
Pre-ageing treatment with a measurable firming effect. Collagen stimulation and dermal redensification have a cumulative effect over several sessions.
07
Seasonal detox
After winter, after periods of intense sun exposure, after periods of stress. A course of three treatments per season helps maintain skin quality.
08
Neck and décolletage
Areas that often show signs of ageing sooner than the face — one extra ampoule covers both the neck and décolletage.
The technology
What NCTF® 135 HA is.
NCTF® 135 HA is a CE-certified biorevitalisation solution from the French company Fillmed, developed in 1978 by Dr Michel Tordjman. The formula combines 60 essential active ingredients — non-cross-linked hyaluronic acid, 12 vitamins, 24 amino acids, 6 co-enzymes, 5 nucleosides, 6 minerals and glutathione — delivered directly into the dermis.
The difference compared to traditional skin boosters lies in the multi-component cocktail of active ingredients: NCTF® does not deliver a single active ingredient, but rather the full range of components, which the skin needs for cell regeneration, collagen synthesis and hydration. Via 40 years of research, which has won several international awards in aesthetic medicine (Best Revitalisation Injectable at AMWC 2023, Skin Hero Award – Product of the Year at the Safety in Beauty Diamond Awards), 98% documented patient satisfaction. It’s not a filler — no change in volume, no change in contours, just the building blocks that the skin is lacking.
AT ALESTETICS®
We apply NCTF® using the Vital Injector 2™ by the Korean company Eunsung Global (since 1995) — a multi-needle system with five needles and an integrated vacuum that precisely controls dosage, penetration depth, pressure and speed. The result: no micro-papules, no wheals, no bruising — unlike traditional needle mesotherapy. Sterile, single-use modules ensure maximum hygiene. At alestetics®, NCTF® is one of the key treatments in our Skin Quality System — often used as a skin primer prior to Vivace® or IPL, or as a layer of active ingredients following a peel.
We apply NCTF® using the Vital Injector 2™ by the Korean company Eunsung Global (since 1995) — a multi-needle system with five needles and an integrated vacuum that precisely controls dosage, penetration depth, pressure and speed. The result: no micro-papules, no wheals, no bruising — unlike traditional needle mesotherapy. Sterile, single-use modules ensure maximum hygiene. At alestetics®, NCTF® is one of the key treatments in our Skin Quality System — often used as a skin primer prior to Vivace® or IPL, or as a layer of active ingredients following a peel.
Verified product information:
Fillmed NCTF® 135 HA — official manufacturer’s website
Vital Injector 2™ by Eunsung Global — Product Data Sheet
What sets us apart
Three reasons why NCTF® works for us.
Mesotherapy hinges on two things: the product and the application. Both of these make all the difference at alestetics® — along with the strategy for integrating NCTF® into the overall treatment system.
Strategy
For us, NCTF® isn’t a standalone treatment — it’s the skin primer.
2–3 NCTF sessions before Vivace® or IPL prepare the skin well. 2–3 sessions after energy-based treatments strengthen and stabilise the results. Combined with BioRePeel® or PRX-T33® in the same session — peel first, NCTF second — it works best because the peel leaves the skin ready to absorb active ingredients.
Comfort
No micro-papules. No bruising. No plaster-like appearance.
Instead of manual single injections, we use the Vital Injector 2™ — a multi-needle system with 5 needles and gentle vacuum suction. The vacuum lifts the skin while dose, depth, pressure, and speed stay precisely controlled. Unlike manual mesotherapy, it leaves no bumps, no wheals, and no bruising — you walk out with a glow, not a treated look.
Science
Developed in 1978. Winner of multiple awards. Facts, not promises.
Developed in 1978 by Dr Michel Tordjman, NCTF® is one of the best-documented mesotherapy formulas worldwide. Backed by over 40 years of research and CE-certified, it won Best Revitalization Injectable at AMWC 2023 and Skin Hero Award – Product of the Year at the Safety in Beauty Diamond Awards, with 98% patient satisfaction in clinical studies.
Combination logic
NCTF® is the skin primer in the system.
NCTF® is one of the few treatments that works before, after and alongside other treatments. It’s the approach that makes the difference — whether used as a standalone treatment, as a primer before energy-based treatments, or as a layer of active ingredients after peels and IPL in the same session.
Same session
Combinations
- AFTER BioRePeel® or PRX-T33®
Exfoliate first, then apply NCTF® — for the best results. After exfoliation, the skin barrier is at its most receptive; active ingredients penetrate deeper than at any other time.
- AFTER HydraFacial™
NCTF® is absorbed particularly effectively by cleansed and exfoliated skin.
- AFTER Stellar M22™ IPL
IPL treats pigmentation and blood vessels, whilst NCTF® delivers a layer of active ingredients immediately afterwards — a powerful combination for a radiant glow and an even complexion.
Always included
At every session
- Custom-made mask
After every NCTF® session — soothes and supports recovery.
- Dermalux™ LED + SPF 50
LED phototherapy immediately after the treatment soothes the skin. Applying SPF 50 at the end provides protection on the day of the session.
With a gap
Not the same session
- Vivace® RF Microneedling (2 weeks apart)
Ideally, 2–3 NCTF sessions prior to Vivace® — Skin Primer. Followed by 2–3 sessions after Vivace® to consolidate the results.
- Volnewmer® RF (2 weeks apart)
Same skin primer approach — NCTF® before and after Volnewmer®, not in the same session.
- PolyPhil™ polynucleotides (2 weeks apart)
Both are active ingredient treatments — we alternate between them rather than combining them in the same session.
Sample plan
Skin renewal with NCTF® as a primer — a typical treatment regimen prior to Vivace® or IPL.
Week 0
Free AURA 3D skin analysis + plan
Weeks 1, 3, 5
NCTF® treatment as a skin primer — 3 sessions every 10–14 days
Week 7
Vivace® RF microneedling or Stellar M22™ IPL
Weeks 9, 11, 13
NCTF® Course 2–3: Consolidating Results
Maintenance
Seasonal update to the Standard Commitment Plan
The personalised plan is created during the free AURA 3D skin analysis — your skin type, previous treatments and goals determine the number, order and appropriate combination of treatments.
The procedure
Here’s how your NCTF® session works.
01
Before treatment
Skin analysis and consultation.
A brief consultation to discuss your skin type, treatment goals and previous treatments. Together, we’ll decide whether to use NCTF® on its own, in combination with a peel, or as a skin primer ahead of an upcoming Vivace® or IPL treatment. For first-time clients, we recommend the free AURA 3D skin analysis beforehand to create a personalised plan.
02
During the session · 45–60 mins
Vital Injector 2™ with vacuum control.
You're lying there, relaxed. The Vital Injector 2™ handpiece gently tightens the skin, the 5-needle system applies NCTF® evenly and precisely. One ampoule treats the the entire face, including the eye area — we take a holistic approach, rather than focusing on specific areas. An additional ampoule is included for the neck and décolletage. You’ll feel a gentle pressure, not a stinging sensation. This is followed by a customised mask, Dermalux™ LED phototherapy and SPF 50.
03
After the treatment
Ready to go out straight away. No micro-papules. No downtime.
Unlike traditional needle mesotherapy, you leave the clinic no micropapules, no wheals, no bruising — a result of the Vital Injector 2™’s precise vacuum control. Make-up can be applied on the same day, but this is not recommended — the skin benefits from being able to breathe. Avoid exercise, hot weather and saunas for 24–48 hours, gentle care, SPF 50 every day. The initial revitalising effect is immediately visible; the full results become apparent over the course of the three-step treatment.
Ready to improve your skin from the inside out?
Book your NCTF® 135 HA session at Zurich HB.
45 to 60 minutes. 60 essential active ingredients delivered directly into the skin matrix — no micro-punctures, no downtime. Use as a skin primer before Vivace® or IPL treatments, or as a restorative treatment. If you’d like a consultation first, the AURA 3D skin analysis is completely free of charge.
alestetics® · Skin Quality Clinic · Konradstrasse 1, 8005 Zurich (main station) · 3 mins from the main station
Frequently asked questions
What clients want to know before their first NCTF® session.
Frequently asked questions about Fillmed NCTF® 135 HA at alestetics® — price, effects, clinical trials, combinations and more.
Is NCTF® a filler? +
No. NCTF® 135 HA is no filler — The hyaluronic acid it contains is not cross-linked and does not add volume. It does not alter your facial features.
NCTF® is a Biorevitalisation solution, which delivers 60 essential active ingredients directly into the skin matrix: building blocks for cell regeneration, collagen synthesis and hydration. The result is better Skin quality — Radiance, firmness, freshness — with no change to facial contours.
How much does NCTF® cost at alestetics®? +
The NCTF® 135 HA treatment costs CHF 300 per ampoule.
One ampoule treats the the entire face, including the eye area — we take a holistic approach, rather than a piecemeal one. For Neck and décolletage an additional ampoule is charged (for both areas combined).
With the Standard Commitment Plan, you get 5 sessions for CHF 1,200 (pay for 4, the 5th is included) — choosing between SkinPen®, BTL Exilis®, and NCTF®. At each visit, we decide together which treatment will help your skin most.
How many sessions will I need? +
The standard protocol at alestetics® is 3 sessions every 10–14 days as a restorative course. Afterwards, we recommend a Maintenance, depending on your skincare goals and the season.
When we use NCTF® as a skin primer before Vivace® or Stellar M22™ IPL, we often plan 2–3 sessions before the energy-based treatment and 2–3 sessions after to consolidate results.
We draw up the personalised plan in the free AURA 3D skin analysis — based on skin type, previous treatments and your goals.
What clinical results have been documented? +
NCTF® is one of the best-documented mesotherapy solutions in the world — backed by over 40 years of research and numerous clinical trials conducted by the manufacturer, Fillmed:
Skin tone +69%
Collagen stimulation +256%
Dermal redensification +54%
Instant glow +119%
Crow's feet -40%
Patient satisfaction 98%
Full list of studies and sources: Fillmed NCTF® 135 HA — official manufacturer’s documentation.
What is the Vital Injector 2™? +
The Vital Injector 2™ is a multi-needle system developed by the Korean company Eunsung Global (since 1995) — with 5 needles and integrated Vacuum. The vacuum gently pulls the skin taut, whilst the dosage, penetration depth, pressure and speed are precisely controlled.
That is why at alestetics® no micropapules, no wheals and no bruising are created — in contrast to traditional needle mesotherapy, which involves individual injections. Sterile, single-use modules ensure maximum hygiene.
Verified product information: Vital Injector 2™ — Eunsung Global Product Data Sheet.
Does the treatment hurt? +
Thanks to the vacuum control of the Vital Injector 2™, the treatment is nearly painless. Instead of single pricks, 5 needles enter simultaneously at a precise depth — you feel light pressure, not sharp stings.
Can I combine NCTF® with Vivace® or IPL? +
Yes — NCTF® is one of the most versatile active ingredient treatments in our Skin Quality System. The combinations vary depending on the treatment:
- Stellar M22™ IPL — the following treatments can be carried out in the same session: IPL treats pigmentation and blood vessels, whilst NCTF® then delivers a layer of active ingredients to soothe and regenerate the skin. A powerful combination for a radiant glow and an even complexion.
- Vivace® RF Microneedling — spaced apart: 2–3 NCTF sessions before Vivace® as a skin primer, and 2–3 sessions after Vivace® to consolidate results. Not in the same session — we space them 2 weeks apart.
- Volnewmer® — spaced apart: Same skin-primer approach as with Vivace® — NCTF® before and after Volnewmer®, not in the same session.
Ideally, in the same session: Start with BioRePeel® or PRX-T33®, then follow with NCTF® — this delivers the best results, as the skin is at its most receptive after the peel.
What sets NCTF® apart from other skin boosters? +
NCTF® differs from standard skin boosters in three key ways:
- 60 active ingredients instead of just one — non-cross-linked hyaluronic acid plus 12 vitamins, 24 amino acids, 6 co-enzymes, 5 nucleosides, 6 minerals and glutathione. The full spectrum of building blocks the skin needs for regeneration.
- Over 40 years of research — developed in 1978 by Dr Michel Tordjman, one of the best-documented mesotherapy products in the world.
- Award-winning product — awarded the title of Best Revitalising Injectable at the AMWC 2023 and as Skin Hero Award – Product of the Year at the Safety in Beauty Diamond Awards.
When is NCTF® not an option? +
NCTF® is not suitable for:
- Active skin infections, herpes or inflammation in the treatment area
- Known allergies to active ingredients
- Autoimmune diseases or active immunotherapy
- Taking blood-thinning medication
- Pregnancy and breastfeeding
- Anyone under the age of 18
If you have any specific medical conditions or are taking medication, we will discuss your suitability on a case-by-case basis during your consultation.
Is there a downtime after NCTF®? +
No, there is no downtime. Thanks to Vital Injector 2™, there is usually no scarring or bruising left; makeup can be applied the same day.
How long does an NCTF® treatment take? +
45–60 minutes, including consultation, mask, Dermalux™ LED and SPF 50.
When will I see results after NCTF®? +
The skin usually looks fresher immediately. The full effect is achieved over the course of 3 sessions spaced 10–14 days apart. Results are individual.
Can NCTF® be applied to the eyes, neck, and neckline? +
Yes, one ampoule (CHF 300) is enough for the entire face, including the eye area. A second ampoule is added for the neck and décolleté together.
Who is NCTF® suitable for – and how often should it be refreshed? +
For those who want more glow and better skin quality without changing volume: for fine lines, for pre-aging and as a refresher. Depending on the skin, we recommend refreshing the series approximately once a month.
Medically reviewed by Alexandra Stroganova, Founder & Pre-Aging Expert · As of: October 2026
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